Been gone too long!!!

It has been far far to long since I have posted, updated/added anything to this site and for that I am truly sorry.  Sorry to myself more than anyone else as this was a passion.
I dare not say that I was too busy, even though I truly was, but rather, I was distracted.  I put up this site with intent of sharing my collected information with others but what I have been busy doing is gleaning new knowledge that seems to change as rapidly as the sun rises and sets.  I was rather overwhelmed to say the least and I felt like there was no way I could keep up.

I have decided that I do not want to give up on this site, rather, I want to make it better, functional and something that others can enjoy, contribute and gain from.  To accomplish this, I am removing the Bulletin Board.  All my time was taken up chasing away bots without any real contribution.  There is a good chance that there were people signing up that may have contributed but, again, chasing the bots away probably caused me to remove legitimate people.  I also want to allow others to contribute to this site.  The invitation is extended to anyone that would like to contribute an article/information.  If you have a topic you would like me to research or if you would like to write on a topic, both can be done.  You will first need to be vetted and your article will need to be reviewed before posting, but I welcome a more diverse group of ideas, articles and writing to this site.

I will allow some advertising, in very limited quantities and not in pop ups, only in side bars.  These will only be for items relating to topics of this site.

The most important point is, please, give me suggestions.  I am open to new ideas and topics as long as they are in some way related around the general topic of life extension.

All the best,



I have set this post to be listed in both Inside Out and Skin Deep because, well, because this stuff helps on both those fronts.

BPC -157 is a synthetic analog of a substance made in your pancreas and has been utilized for a few years now in wound healing.  It has been added to gel packs that are used by EMT for burn victims and it is a new additive to stomach ulcer medication as it is able to heal an ulcer in 5 days.
There is a lot of new testing and experimentation going on with this protein both in the scientific community and the personal community.  There are several completed and on going research around tendon healing.  The severed tendon of a rat can grow back together, in short order, utilizing BPC-157.  In one of those studies, the nerves for the foot of the rat were accidentally cut along with the tendon and the rat, not being able to feel his foot, chewed 1/2 of it off.  As the results required were with regards to the tendon, not the foot the rat was kept in the study and at the end of the study it was found that the rat had regrown the missing part of its foot.

BPC-157 has been studied and put in field testing by the Chinese Army to allow quick healing from injuries.  Of course, this is meant to get the solders back out on the field as soon as possible but despite its indented use in the study, the potential other uses are mind boggling.

BPC-157 has been tested on and found to reduce and/or completely eliminate the swelling caused in the intestines from Crones disease.  Not just Crones either, it can have this effect from any IBS.

If you think about where BPC-157 is produced in the body and know what it does, it makes sense that this is a “healing” substance naturally produced by our body and pumped into the digestive tract.  Why there?  Well, it is very stable in the digestive tract and therefore is able to enter the blood stream and go through out the body to aid in healing anywhere.  Technically, this should aid in the healing of all internal organs, even the brain and nerves.  In fact, it has already been trialed on liver damage and found to be able to reverse  excessive alcohol damage.

It is being used on the black market, in inject-able form, by body builders because it can heal muscle very fast.  After breaking down muscle in weight lifting, the BPC-157 can heal the muscles quickly allow those same muscles to be broken down for building again faster than ever before.

It only makes sense that as we age, with all other functions and organs of our body, our pancreas also does not produce as much BPC-157.  It is well documented that as we age we do not heal as fast.  Given that this is a substance native to our bodies, I don’t see why this should not be fast tracked as a supplement but, given the track record of those who make these judgments (FDA), I doubt we will see it any time soon.  Heaven forbid that we should have people be healthier and live longer, right?  Too much lost pharmaceutical revenue.


It appears that there is a new kid on the block, that is to say, new as in the knowledge of its benefits.
is a precursor to NADH and has a lot of its own benefits to the body in addition to NADH but lets talk about NADH first.
NADH (vitamin B3), in nature, is found in all the living cells of plants, animals and humans. All 60 trillion cells found in the human body contain it. Brain cells contain about 50 mcg of NADH per gram of brain tissue. Heart cells contain 90 mcg of NADH per gram of heart tissue. Red blood cells contain 4 mcg of NADH. The more energy a cell needs, the higher the concentrations of NADH.
NADH is also known as co-enzyme #1 because it is top ranked over all other co-enzymes. This includes a ranking over the well known co-enzyme Q-10.
Co-enzymes are essential components of enzymes which are necessary for every metabolic reaction in our body. Co-enzymes also form other molecules in cells. Cells need these molecules to perform their functions. Without co-enzymes, the human machine does not work and all cell processes stop.
In our bodies, NADH is destroyed or depleted. The world’s most renowned doctors and scientists don’t know why NADH is being depleted from our body’s. Somehow stress, fatigue, old age, environmental chemicals, and disease may damaged or deplete our NADH supplies. Even with enough glucose and oxygen (fuel and air) some cellular engines don’t produce enough power.
We can obtain some NADH from our diet or from a dietary supplement. Either way NADH has to come from outside the body. The body doesn’t make NADH. The problem is, NADH is destroyed almost instantly by the digestive tract in humans and thus what we can get from our food or from the multitude of supplements you can find all over the net is not going to be enough to supplement our needs.

In comes NAD+
NAD+, is a redox pair to NADH and is not broken down in the digestive tract like NADH is. NAD+ activates SIRT1 (sirtuin 1). SIRT1 is the most extensively studied of the seven-member family of mammalian sirtuins. SIRT1 couples NAD+ hydrolysis with protein deacylation. It is a member of the class III family of histone deacylases and regulates DNA repair and gene transcription. SIRT1 has profound beneficial effects on renal diseases including renal aging, diabetic nephropathy, and the response to unilateral ureteral obstruction. Furthermore, SIRT1 has recently received much attention because it has salutary effects on metabolic syndrome and may mediate some of the life-prolonging effects of caloric restriction.
NAD+ is an essential cofactor for the poly-(ADP-ribose) polymerases (PARPs). These enzymes attach negatively charged polymers of ADP-ribose to proteins and change their function; in this way, PARP1 regulates apoptosis, DNA repair, necrosis, and gene transcription, including transcription of proinflammatory genes. This regulation is germane to this discussion because PARP1 is required for cisplatin nephrotoxicity.

So why am I mentioning NADH if this topic is about NAD+? Well, as mentioned above, because NAD+ is a redox pair of NADH, that means that after NAD+ has carried out its function in your body it will convert to NADH and after NADH has carried out its function, will convert back to NAD+. This conversion, however, is not on par. It will continually reduce with the eventual destruction and elimination of the co-enzymes so it is necessary to continue intake and up regulation of both. As mention previous, however, taking NADH orally will not help because it is destroyed by the intestinal tract.

So, stop looking for Vitamin B3 and start looking for supplies of NAD+.